Sitagliptin counteracts seasonal fluctuation of glycemic control
نویسندگان
چکیده
منابع مشابه
Sitagliptin Successfully Ameliorates Glycemic Control in Werner Syndrome With Diabetes
Werner syndrome (WS) is an autosomal recessive disorder caused by a mutation in the WRN gene, and it is considered to be a representative type of progeroid syndrome (1). Patients with WS often exhibit insulin resistance, which is associated with the accumulation of visceral fat and disadipocytokinemia. We and others have previously reported that pioglitazone, a peroxisome proliferator–activated...
متن کاملEffects of sitagliptin beyond glycemic control: focus on quality of life
BACKGROUND Recently, incretin hormones, including glucagon-like peptide-1 (GLP-1) analogue and dipeptidyl peptidase-4 (DPP-4) inhibitor, have been found to regulate glucose metabolism. The aim of this study was to elucidate the efficacy and safety of the clinical usage of DPP-4 inhibitors in Japan. METHODS This study was designed as a prospective, open-label, multi-center trial. Patients with...
متن کاملThe combination of colesevelam with sitagliptin enhances glycemic control in diabetic ZDF rat model.
Bile acid sequestrants have been shown to reduce glucose levels in patients with type 2 diabetes. We previously reported that the bile acid sequestrant colesevelam HCl (Welchol) (COL) induced the release of glucagon-like peptide (GLP)-1 and improved glycemic control in insulin-resistant rats. In the present study, we tested whether adding sitagliptin (Januvia) (SIT), which prolongs bioactive GL...
متن کاملSitagliptin added to voglibose monotherapy improves glycemic control in patients with type 2 diabetes
AIMS/INTRODUCTION Type 2 diabetes mellitus is a progressive disease that frequently requires patients to use more than one oral antihyperglycemic agent to achieve adequate glycemic control. The present multicenter, randomized study assessed the efficacy and safety of the addition of sitagliptin to ongoing voglibose monotherapy (0.2-0.3 mg three times daily) in Japanese patients with type 2 diab...
متن کاملSeasonal fluctuation of Plasmodium falciparum gametocytaemia.
Two numerically minor components of Plasmodium falciparum prevalence--gametocytaemia and trophozoite densities greater than 99/500 white blood cells--displayed an annual cycle that reflected the seasonal abundance of infective Anopheles dirus at a hyperendemic focus in Thailand, even though the gross monthly prevalence for combined ages remained stable. Gametocyte prevalence rose more than 300%...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: World Journal of Diabetes
سال: 2012
ISSN: 1948-9358
DOI: 10.4239/wjd.v3.i6.118